Menopause Update Feb 2010

In this edition of Menopause Update the following new articles are available for download: February 2010

	Assisted Reproductive Technology (ART) in the maturing woman Fecundity significantly declines with increasing maternal age.1-3 As this loss of reproductive potential increases from just 10% at 34 years of age to over 85% by the age 44 years.1 The factors associated with this of loss of reproductive potential include rapid loss of oocytes (which cannot be compensated by Controlled Ovarian Hyper stimulation- COH), an increase in oocyte nuclear abnormalities and aneuploid (resulting decrease in a fertility index, pregnancy rate and increased fetal loss).4 Other reported factors include ... READ MORE
	The Management of the Ageing Male with special reference to the late onset of hypogonadism Both health and ageing are social and cultural constructs in addition to being biologically determined. There are three basic sources of differences in healthy ageing: hereditary determinants, socio-economic circumstances, as well as life style and other behavioural factors. Gender differences span all three domains. Cultural and political factors also influence the health of older men. One has also to recognise that ... READ MORE
	Premature Ovarian Failure Natural menopause occurs approximately at 50 ± 4 years. Premature ovarian failure (POF) is the development of amenorrhoea for at least 4 months due to cessation of ovarian function before the age of 40 years. The diagnosis is based on elevated FSH levels in the menopausal range (above 40IU/l) detected on at least two occasions at 4-6 weeks apart. There are no accurate estimates of the prevalence of POF. Most reports merely give the percentage of women with infertility, oligomenorrhoea, or amenorrhoea presenting for evaluation. It is an uncommon disorder affecting ... READ MORE
	Preventing Type 2 Diabetes - a work in progress A dramatic increase in the prevalence of T2DM has occurred over the last few decades. In global terms this is projected to lead to an estimated increase from 157 million diabetics worldwide in 2000 to over 350 million by 2025.1,2 This increase has not been evenly distributed when nations are compared with each other, nor is the increase in prevalence evenly distributed amongst those that live in these various countries. A comparison, for example, of the overall prevalence in diverse countries such as USA, Tanzania, Australia, Japan and Mauritius varies form 3 - 18% and illustrates this point convincingly. The difference... READ MORE